What is the most soluble solute I can get to dissolve it in water?
Q. It has to be extremely soluble to dissolve 100% in water, which means that is had to be polar
Asked by nico - Thu May 24 00:14:44 2007 - - 2 Answers - 0 Comments

A. Since you don't say if the solute should be liquid or solid, two answers are ethanol and methanol. Both are "miscible" in water, meaning they dissolve in each other in all proportions. That's infinite solubility; it's impossible to be more souble than that. Off the top of my head, the only solid material that I can think of that displays miscibility behavior with water is poly(acrylic acid).
Answered by Schmedley - Thu May 24 08:03:33 2007

How do I determine what cells are secreting a soluble substance within a tissue?
Q. Suppose you have a tumor, and you know the tumor is enriched for a particular soluble factor--how do you figure out which cells are secreting the soluble factor? I don't need detailed instructions, just tell me what method to use and I can look up the rest. My background is all in vitro biochemistry, so I'm a bit out of my element here with living cells.
Asked by grimmyTea - Mon Apr 16 01:00:21 2007 - - 1 Answers - 0 Comments

A. I think it depends on the nature of the cell population to investigate (whether is is "mobile" or bound to a body mass. The general idea is to use fluorescent or radioactive dyes that can be monitored with imaging systems in vivo. A good example is given by Injections of a radioactive dye for sentinel lymph node identification, by the use of a radiolabeled, low molecular weight dye (e.g., .sup.125I-labeled methylene blue). This radiolabled dye is mixed with an unlabeled, similar molecular weight dye (e.g., isosulfan or methylene blue). The mixture is injected at the time of surgery, and rapidly migrates to reach the lymph nodes in less than 20 min, more preferably in less than 15 min and most preferably in less than 10 min. Optical whole- [cont.]
Answered by lovely green eyes - Mon Apr 16 01:34:34 2007

Why is cannabinol very slightly soluble in methyl alcohol at room temperature?
Q. I know that both methyl alcohol and cannabinol are both alcohols but Can you help me understand why cannabinol is just a little soluble in methyl alcohol at room temperature? Is it a gas at that temperature?
Asked by angelic91 - Tue Jan 13 11:36:00 2009 - - 2 Answers - 0 Comments

A. Nope most definitely a solid at RT. Take a look at the structure of the compound. It has 3 rings total, two of which are phenyl rings, 3 methyl groups and a pentyl group while there is only one OH. That is a lot of non-polar groups for just one polar group. This is why it is sparingly soluble in MeOH at RT, it really is not a very polar molecule (the general rule of thumb is 5 C's for every polar group for the molecular to be considered polar, this of course is a generalization).
Answered by Jeffrey Struss - Tue Jan 13 11:46:03 2009