Solubility is the property of a solid, liquid, or gaseous chemical substance called solute to dissolve in a liquid solvent to form a homogeneous solution. The solubility of a substance strongly depends on the used solvent as well as on temperature and pressure. The extent of the solubility of a substance in a specific solvent is measured as the saturation concentration where adding more solute does not increase the concentration of the solution.
The solvent is generally a liquid, which can be a pure substance or a mixture.[1] One also speaks of solid solution, but rarely of solution in a gas (see vapour-liquid equilibrium instead)
The extent of solubility ranges widely, from infinitely soluble (fully miscible[2] ) such as ethanol in water, to poorly soluble, such as silver chloride in water. The term insoluble is often applied to poorly or very poorly soluble compounds.
Under certain conditions the equilibrium solubility can be exceeded to give a so-called supersaturated solution, which is metastable.[3]
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PR Newswire (press release), NY
SIMPONI is a new, human anti-tumor necrosis factor (TNF) monoclonal antibody that was generated by Medarex's UltiMAb(R) technology that targets and neutralizes both the soluble and membrane-bound forms of TNF-alpha. Regulatory applications seeking ...
